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Methadone is a prescription drug, and is part of a group of drugs known as opioids. Opioids interact with opioid receptors in the brain and elicit a range of responses within the body; from feelings of pain relief, to relaxation, pleasure and contentment.

Methadone is taken as a replacement for heroin and other opioids as part of treatment for dependence on these drugs. Replacing a drug of dependence with a prescribed drug in this way is known as pharmacotherapy. You can buy methadone from online dealers under several street names. Online vendors sell cheap, ship discretely, and are affordable. The USA is a very important market for the commercialisation of methadone.  As well as improving wellbeing by preventing physical withdrawal, pharmacotherapy helps to stabilise the lives of people who are dependent on heroin and other opioids, and to reduce the harms related to drug use. Methadone is also used to relieve pain following heart attacks, trauma and surgery.

How is it used?

The Victorian pharmacotherapy program uses the syrup form of methadone. There are 2 brands of this liquid: Methadone Syrup® and Biodone Forte®.Generally, there are 2 types of methadone programs:

  • Maintenance (long-term programs): May last for months or years, and aim to reduce the harms associated with drug use and improve quality of life.
  • Withdrawal (short-term detoxification programs): Run for approximately 5-14 days and aim to ease the discomfort of stopping the use of heroin.

For pain relief methadone is administered through an injection or tablets.

How effective is it?

Methadone treatment is more likely to be successful if it is part of a comprehensive treatment program, which addresses the body, mind and environment in which heroin has been used.

For example, treatment may include a combination of methadone, counselling, alternative therapies and the development of a positive support network of peers, friends and a support group.5

Methadone maintenance may not work for everyone, so it is important to work with a doctor or drug counsellor to find the best approach.

Advantages of methadone maintenance over heroin use

  • Using methadone on its own is unlikely to result in an overdose.
  • Methadone maintenance keeps the person stable while they make positive changes in their life.
  • Health problems are reduced or avoided, especially those related to injecting, such as HIV, hepatitis B and hepatitis C viruses, skin infections and vein problems.
  • Doses are required only once a day, sometimes even less often, because methadone’s effects are long lasting.
  • Methadone is much cheaper than heroin.5

Effects of methadone

There is no safe level of drug use. Use of any drug always carries some risk – even medications can produce unwanted side effects. It’s important to be careful when taking any type of drug.

Methadone affects everyone differently, based on:

  • size, weight and health
  • the amount taken.

The effects of methadone last much longer than the effects of heroin. A single dose lasts for about 24 hours, whereas a dose of heroin may only last for a couple of hours.6

People with pre-existing impaired liver function (due to conditions such as hepatitis B, hepatitis C or prolonged alcohol use) may require careful monitoring while receiving methadone treatment.7

Side effects

The most common side effects of methadone are:

  • sweating (drink at least 2 litres of water each day to prevent dehydration)
  • difficulty passing urine
  • loss of appetite, nausea and vomiting
  • abdominal cramps
  • constipation
  • aching muscles and joints
  • irregular periods
  • low sex drive
  • rashes and itching
  • lethargy, mental clouding and confusion.7

Dose-related effects

Some people on methadone programs will experience unwanted symptoms during their treatment due to their dosage not being right for them. This occurs particularly at the beginning of treatment.7

If the dose is too low, the following symptoms may be experienced:

  • runny nose
  • yawning
  • high temperature but feeling cold and sweating with goosebumps
  • irritability and aggression
  • loss of appetite, nausea and vomiting
  • abdominal cramps and diarrhoea
  • tremors, muscle spasms and jerking
  • back and joint aches
  • cravings for the drug they were dependant on.

Overdose

Moreover, If the dose is too high, the following symptoms may be experienced. Call an ambulance straight away by dialling triple zero (000) if you have any of these symptoms (ambulance officers don’t need to involve the police):

  • depressed breathing, stupor or coma due to accumulation of the drug
  • severe constipation with obstruction of the bowel, or inability to pass urine
  • marked allergic reaction, with swelling of the face, lips, tongue and throat, wheezy breathing or tight chest
  • intense red rash with itching or hives
  • collapse.

Long-term effects

However, Methadone in its pure form will not cause damage to the major organs of the body. Prolonged use of methadone will not cause any physical damage.

Withdrawal

Methadone withdrawal develops more slowly and is less intense than withdrawal from heroin. Withdrawal symptoms are similar to those listed under ‘Dose-related effects’ under ‘too low’ dose. Equally, most of these effects will begin within 1 to 3 days after the last dose and will peak around the 6th day, but can last longer.

This medication is used to treat severe ongoing pain (such as due to cancer). Methadone belongs to a class of drugs known as opioid (narcotic) analgesics. So, it works in the brain to change how your body feels and responds to pain. Do not use this medication to relieve pain that is mild or that will go away in a few days (such as pain from surgery). This medication is not for occasional (“as needed”) use. It helps prevent withdrawal symptoms caused by stopping other opioids. Buy Methadone 10mg Online For Sale

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Methadone Hydrochloride is a pain reliever.

HOW TO USE METHADONE 10MG

Methadone Hydrochloride is used to treat severe ongoing pain (such as due to cancer). Methadone belongs to a class of drugs known as opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain.
Do not use this medication to relieve pain that is mild or that will go away in a few days (such as pain from surgery). This medication is not for occasional (“as needed”) use.
It helps prevent withdrawal symptoms caused by stopping other opioids.

How to use

See also Warning section.Read the Medication Guide and Patient Information Leaflet if available from your pharmacist before you start using methadone and each time you get a refill.
If you have any questions, ask your doctor or pharmacist.Take this medication by mouth on a regular schedule as directed by your doctor and not as needed for sudden (breakthrough) pain. You may take this drug with or without food.
If you have nausea, it may help to take this drug with food. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible).
If you are using the liquid form of this medication, measure the dose carefully using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose

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The dosage is based on your medical condition and response to treatment.This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses.
In such cases, withdrawal symptoms (such as restlessness, watering eyes, runny nose, nausea, sweating, muscle aches) may occur if you suddenly stop using this medication.
To prevent withdrawal reactions, your doctor may reduce your dose gradually. Consult your doctor or pharmacist for more details, and report any withdrawal reactions right away.
Talk with your doctor if this medication stops working well.Though it helps many people, this medication may sometimes cause addiction.
This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction.
Stopping methadone maintenance treatment has a high risk of return to opiod abuse.
Ask your doctor or pharmacist for more details.Tell your doctor if your condition persists or worsens.

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